Saturday, October 16, 2010
sory lame x de citer
salam semua.... sory la lame x update citer yea.... bukannye ape cibuk sikit sbb nak final exam ( sibuk ker).... urm... mmg tgh banyak citer nie.... tapi nanti petang org citer yea,... nak study jap..... k...
Friday, October 8, 2010
dokter2
salam.... hehehehhe
korang bace x paper utusan semalam??? ( 07 oct 2010) page 12yang ruangan forum tu... hahahahah yg ade komen2 sikit tu.... meh lah aqu tunjuk keratan yng mane satu... hehehhe
DOKTER 'AGEN' SEBAR PENYAKIT SECARA TIDAK LANGSUNG
ha... org yang komen tu dio antar surat kat surat kabar lah,,... die tegur dokter... pi kantin pakai kot lab... sedangkan kot lab yg dokter pakai tu wat pi jumpa patient... kantin tu tempat awam,... org duk makan... mesti micro2 from patient melekat kat lab kot diorang kan... sory yea dokter2 sekalin... mmg ah... kalu kite tgk dokter... bangga kan,,... senyum melebar kite jumpe diorang... ye lah dokter kottt... tapi... aqu powm setuju dengan penulis surat tu.... apesal dokter bawa baju lab kot ke kantin... n kalu x silap aqu... kot makmal a.k.a kot dokter.. hahaha... x leh bawa kat tempat public...
aqu powm pernah tgk ngan mate sendiri... sbb aqu belajo kat usmkk kampus kesihatan.... so adelah budak2 medik a.k.a dokter... ade sampai diorang naik moto nak balik umah or asrama powm pakai lab kot tu..... kononye x nak buh dalam bag... nanti kedut....
kate belajor anatomi... x kan x tau.. yg diorang pakai lab kot sampai ke naik motor or jalan kaki(biase student medic le... gaji x dapat lagi... naik motor dulu... heheheh) or diorang pi mane2 lah tmpat publik pakai labkot... of course diorang akan bawe microb2 yg kotor n pi jumpe patient... kan.. kan... kan...
so... saya harap doktr2 kite kat malaysia nie pikir lah yea... mmg isu kecik jer kot... tapi yea lah.... mmg bangga wei pakai lab kot tu... aqu yg nursing nie ade gak labcot... pakai dalam makmal je lah... siap amik gambo pah tag dalam f.b... konon nye dokter lah.... hahahahahaha.. harap2 dokter2 sekalian dapat mimikirkannye and amik lah tindakan yea...
ye dokter.... ok.... jangan marah ye.... kite saling tegur menegur lah yea.... heheheheheheheh
korang bace x paper utusan semalam??? ( 07 oct 2010) page 12yang ruangan forum tu... hahahahah yg ade komen2 sikit tu.... meh lah aqu tunjuk keratan yng mane satu... hehehhe
ha.... yang nie...... ( keratan akhbar utusan o7 oktober 2010) |
ha... org yang komen tu dio antar surat kat surat kabar lah,,... die tegur dokter... pi kantin pakai kot lab... sedangkan kot lab yg dokter pakai tu wat pi jumpa patient... kantin tu tempat awam,... org duk makan... mesti micro2 from patient melekat kat lab kot diorang kan... sory yea dokter2 sekalin... mmg ah... kalu kite tgk dokter... bangga kan,,... senyum melebar kite jumpe diorang... ye lah dokter kottt... tapi... aqu powm setuju dengan penulis surat tu.... apesal dokter bawa baju lab kot ke kantin... n kalu x silap aqu... kot makmal a.k.a kot dokter.. hahaha... x leh bawa kat tempat public...
aqu powm pernah tgk ngan mate sendiri... sbb aqu belajo kat usmkk kampus kesihatan.... so adelah budak2 medik a.k.a dokter... ade sampai diorang naik moto nak balik umah or asrama powm pakai lab kot tu..... kononye x nak buh dalam bag... nanti kedut....
kate belajor anatomi... x kan x tau.. yg diorang pakai lab kot sampai ke naik motor or jalan kaki(biase student medic le... gaji x dapat lagi... naik motor dulu... heheheh) or diorang pi mane2 lah tmpat publik pakai labkot... of course diorang akan bawe microb2 yg kotor n pi jumpe patient... kan.. kan... kan...
so... saya harap doktr2 kite kat malaysia nie pikir lah yea... mmg isu kecik jer kot... tapi yea lah.... mmg bangga wei pakai lab kot tu... aqu yg nursing nie ade gak labcot... pakai dalam makmal je lah... siap amik gambo pah tag dalam f.b... konon nye dokter lah.... hahahahahaha.. harap2 dokter2 sekalian dapat mimikirkannye and amik lah tindakan yea...
ye dokter.... ok.... jangan marah ye.... kite saling tegur menegur lah yea.... heheheheheheheh
Thursday, October 7, 2010
lawatan air loji chicha
sebenarnye aqu pi lawatan loji air chicha sbb aqu nyer silibus sosiology in nursing... hak2.... wajib kot... kalu x pi... kene potong markah.... haha so pakse rela pi nie... sebonarnyo kitorng pi nie 3 bulan yg lepas... tapi baru aqu nak shred... sbbnyer... baru tahu nak wat blog... hahaha... urmm...
kitorg pi naik bus usm ah...tolak kul 9... ingat lame...rupenyer.... 5 minit jer.... x puas lagi aqu naik bas tu.. hak hak... n than kitorg sampai lah saner.. kelantan water sdn bhn chicha... hehehe... a.k.a. kirenyer nie anak syarikat kerajaan negeri kelantan lah...(rasenyr x yah sebut pun korang tahu parti mmrintah kat sini kan... hahhha).. sume bangunan dia warne hijau.. tunjuk gamq sikit... hihihihj
pastu kitorag di bagi lah taklimat... n dio terngkan lah proses2 air nie... sampai lah paip kat umah... tapi aqu hairan an pilik... macam mane kawasan kubang jerian nie and certain tempt dia punyer air paip karat gile... dia punyer proses chey wah... bukan lagi bergaya kot... aleh2 dapat yg karat.. kitorang tanye lah soklan kat dio punye pro kot... kenape air tempat kitorang karat gile... n dia jawabbbbbbbbbb... salah satu faktornye sbb diorang x de saingan... and melibatkan kos... yang aqu benggangnye... x de saingan........... org patutnye bagi perkhidmatan baik giler lah dah ko yang monopoli kan... kalu x caye... nah bukti air sekotor mane yg penah kitorang dapat.......
urmm... dah lah.. malas nak citer pasal kualiti air nie... menyakitkan hti jer kan.. kan... kan....
ok..pas wat lawatan ke loji2... kitoang pun balik... no nak dijadikan citer mesti kitorang kene wat report kan... report group lah... tapi jadi kije individu kottttt... geram doh... aqu sekok2 wat report tu.. diorang wat gak mule2.. and hato... kene reject... pastu aqu wat lah sekok2... yang wat kene reject tu... aqu yang duk taip gak... bincang satu duo page jer... n then aqu wat... kes ngungkit dah nie... tapi ape aqu kisah dari korang x wat kije kan... kan.... kan...
ha... nie lah report aqu... tgk ah kot2 korang nak wat contoh wat report ke... chey wahhhhhhh... hahahaa.. ops2.... sebelum tu... nie ade gamaq skit2... hehehe
kitorg pi naik bus usm ah...tolak kul 9... ingat lame...rupenyer.... 5 minit jer.... x puas lagi aqu naik bas tu.. hak hak... n than kitorg sampai lah saner.. kelantan water sdn bhn chicha... hehehe... a.k.a. kirenyer nie anak syarikat kerajaan negeri kelantan lah...(rasenyr x yah sebut pun korang tahu parti mmrintah kat sini kan... hahhha).. sume bangunan dia warne hijau.. tunjuk gamq sikit... hihihihj
ha.. nie diaaa... tangki jer putih.... eh.. betullah.... hahaha |
pastu kitorag di bagi lah taklimat... n dio terngkan lah proses2 air nie... sampai lah paip kat umah... tapi aqu hairan an pilik... macam mane kawasan kubang jerian nie and certain tempt dia punyer air paip karat gile... dia punyer proses chey wah... bukan lagi bergaya kot... aleh2 dapat yg karat.. kitorang tanye lah soklan kat dio punye pro kot... kenape air tempat kitorang karat gile... n dia jawabbbbbbbbbb... salah satu faktornye sbb diorang x de saingan... and melibatkan kos... yang aqu benggangnye... x de saingan........... org patutnye bagi perkhidmatan baik giler lah dah ko yang monopoli kan... kalu x caye... nah bukti air sekotor mane yg penah kitorang dapat.......
bukan photo edit yea.. singki nie dia punyer ounca air from air kelantan lah... plik kan.......... |
ok..pas wat lawatan ke loji2... kitoang pun balik... no nak dijadikan citer mesti kitorang kene wat report kan... report group lah... tapi jadi kije individu kottttt... geram doh... aqu sekok2 wat report tu.. diorang wat gak mule2.. and hato... kene reject... pastu aqu wat lah sekok2... yang wat kene reject tu... aqu yang duk taip gak... bincang satu duo page jer... n then aqu wat... kes ngungkit dah nie... tapi ape aqu kisah dari korang x wat kije kan... kan.... kan...
ha... nie lah report aqu... tgk ah kot2 korang nak wat contoh wat report ke... chey wahhhhhhh... hahahaa.. ops2.... sebelum tu... nie ade gamaq skit2... hehehe
letih round minum air dulu kan... hehehehe |
PUSAT PENGAJIAN SAINS KESIHATAN
KAMPUS KESIHATAN
DIPLOMA IN NURSING
STUDENT NAME:
MUHAMMAD AZIM BIN AZMAN
MOHD NADZMI BIN ROSLAN
SARMILAN A/L MURUGIAH
NURUL HUSNA BINTI RAHIM
NURUL AIN ASHIKIN BINTI LOUT
NURUL FATIN WAHIDA BINTI AIDIL
NURUL AIN BINTI MOHD NIZAM
NUR AMIRA SHAMSHILLA BINTI MOHD SHAMSUL BAHRI
NURSAKINAH BINTI MOHD ROSLI
COURSE: DGN105/3 SOSIOLOGY IN NURSING
TITLE: LOPORAN LAWATAN KE LOJI AIR CHICHA
DATELINE: 02/08/2010
DATE SENT: 15/08/2010
TUTOR’S NAME: FAZDILLAH HUSIN
TAJUK : LAPORAN LAWATAN KE LOJI AIR CHICHA
NAMA PENULIS : MUHAMMAD NADZMI BIN ROSLAN
DISEDIAKAN UNTUK: PUAN FADZILAH
TARIKH : 2 OGOS 2010
1.0 PENGENALAN
Lawatan ke Loji Air Chicha ini dilakukan untuk memenuhi silibus mata pelajaran DGN 105 sosiologi dalam kejururawatan. Selain itu lawatan ini juga mempunyai objektif tersendiri iaitu, untuk mengenal pasti sumber air yang digunaka, menjelaskan kaedah rawatan yang digunakan, menerangkan kesan pencemaran air ke atas kesihatan dan menerangkan kepentingan air yang dirawat untuk kesihatan.
2.0TUJUAN
Tujuan laporan ini ditulis adalah untuk:
2.1 Melaporkan segala aktiviti dan maklumat yang kami dapat sepanjang Lawatan ke loji air chicha ini dijalankan.
2.2 Selain itu laporan ini juga ditulis bagi memenuhi syarat bagi subjek DGN105 sosiologi dalam kejururawatan.
3.0 SINOPSIS
3.1 Pada 2 ogos 2010 pelajar diploma kejururawatan telah mengadakan lawatan ke Loji Air Chicha. Kami seramai 89 orang termasuk 2 orang pensyarah sebagai pengiring bertolak dari USM Kubang Kerian pada jam 9.15 a.m dengan menaiki dua buah bas USM. Perjalanan kami ke sana memakan masa selama 15 minit.Kami tiba di Loji Air Chicha tepat pada jam 9.30 a.m. Setibanya kami disana, kami telah disambut oleh En Azhari Abd Rahman iaitu Penyelia Loji Air Chicha serta kakitangan-kakitangan yang lain. Kami telah berada disana selama 2jam 30 minit dan bertolak pulang ke kampus kesihatan usm pada pukul 12 tengahhari dan sampai ke kampus pada pukul 12.30. Manakala ada juga pelajar sampai ke kampus pada pukul 1.30 tengahhari kerana sebuah bas daripada dua buah bas yang menghantar kami lewat tiba atas sebab – sebab yang tidak dapat dielakan.
4.0 isi perbincangan
4.1 Antara objektif lawatan ini ialah yang pertama; untuk mengenal pasti sumber air yang digunakan. Sumber air yang digunakan loji rawatan air chicha, sumber air mentah dari tujuh medan telaga iaitu, Pasir Tumbuh, Pasir Hor, Padang Penyadapan, Kubang Kerian, Kenali, Chicha dan Seribong.
4.1.1Objektif kedua, menjelaskan kaedah rawatan yang digunakan. Air yang diperolehi diproses melalui lima peringkat iaitu melalui; pertama pengudaraan air, pengentalan, pemendapan, penapisan dan pembasmian kuman.
4.1.2Objektif ketiga, menerangkan kesan pencemaran air ke atas kesihatan. Antara penyakit bawaan air ialah, taun, cirit birit, keracunan makanan, kepialu, dan lain- lain.
4.1.3Objektif terakhir ialah menerangkan kepentingan air yang dirawat untuk kesihatan.
4.2 Kemudian, kami telah dibahagikan kepada dua kumpulan.
4.2.1 Kumpulan pertama diberi taklimat terlebih dahulu
4.2.2 Semasa taklimat, kami diberi penerangan tentang cara-cara pemprosesan air, serta dua buah tayangan video mengenai sejarah Syarikat Air Kelantan sdn. bhd. dan langkah pemprosesan air dilakukan
4.2.4Manakala kumpulan kedua dibawa melawat ke kawasan rawatan air sementara menunggu taklimat untuk kumpulan satu selesai.Kami juga dibawa melawat ke kolam-kolam air yang sedang diproses.Terdapat banyak kolam yang dibahagikan kepada beberapa bahagian tertentu.Terdapat kolam yang mempunyai kedalaman lebih kurang sepuluh kaki.Kami juga telah diberi penerangan tentang fasa-fasa pemprosesan air.Di sana terdapat sebuah bilik yang mengandungi sepuluh alat kawalan air yang berfungsi untuk membuka pintu laluan air.
4.3 Antara proses yang telah dilakukan untuk memproses air yang di salurkan untuk pengguna ialah Pengudaraan, Pengentalan dan pengumpulan, Pemendapan, Penapisana dan Pengklorinan
4.3.1 Proses pengudaraan ialah proses air mentah disentuh secara dekat oleh udara bagi membebaskan gas – gas atau bahan meruap yang beracun
4.3.2 Proses Pengentalan dan Pengumpulan pula ialah proses dimana satu bahan kimia dicampurkan kedalam air mentah dan membuatkan bahan – bahan halus di dalam air melekat di antara satu sama lain apabila berlaku sentuhan dan membentuk jisim – jisim kental yang sederhana besar ( sub microscopic)
4.3.3 Manakala proses Pemendapan pula, ialah proses untuk membuang atau mengasingkan flok yang telah terbentuk dari air dan juga untuk mendapatkan air yang lebih jernih sebelum ditapis. Tiub Lamella digunakan dalam pengasingan floc bagi proses penjernihan
4.3.4 Seterusnya proses Penapisan yang memerangkap baki – baki floc yang terlepas dari tangki mendap. Menggunakan penapis gravity 2 lap (Penapis Pasir)
4.3.5 Akhir sekali ialah proses pengklorinan. Proses yang melibatkan pembasmian kuman, klorin dimasukan ke dalam air untuk membunuh bakteria berbahaya
4.4 Syarikat Air Kelantan diterajui oleh Y.A.B DATO’ TUAN GURU NIK AZIZ NIK MAT. Loji Rawatan Air Chicha yang ditubuhkan pada julai 2003 dan mengambil kos sebanyak RM80 juta seluas 4.2 hektar.
4.4.1Tangki-tangki air di Loji Rawatan Air Chicha di bersihkan sebulan sekali bagi memastikan air yang dibekalkan terjamin kebersihannya. Air yang dirawat oleh Loji Rawatan Air Chicha diagihkan kepada sepuluh kawasan iaitu Kawasan Perindustrian Pengkalan Chepa, Kemumin, Sabak, Kubang Kerian, Peringat, Melor, Perol, Pasir Hor, Batu 4 dan sebahagian Bachok.
4.4.2 Kapasiti Rekabentuk Loji Rawatan Air Chica ialah 84MLD dan kapasiti pengeluaran semasa ialah 62 MLD.
4.4.3 Loji Rawatan Air Chicha telah menggunakan sistem rawatan air yang lengkap serta mempunyai sistem kawalan berkomputer, SCADA. Loji pertama di negeri Kelantan yang menggunakan ‘lamella plate’
4.4.4 Syarikat air kelantan mempunyai dua puluh satu loji yang menggunakan air sungai manakala tujuh buah lagi loji air syarikat ini menggunakan air bawah tanah
4.5 Berikut adalah keputusan ujian tapak (GI) di Loji Rawatan Air Chicha
PARAMETER | RAW WATER | TREARED WATER | LIMIT WHO (TREATED WATER) |
Pre-chlorine (mg/l) | - | 1.50 | >0.2 |
Turbidity | 5.0 | 0.5 | 5.0 |
pH | 5.80 | 7.00 | 6.5 – 9.0 |
Colour (TCU) | 15 | 0 | <15 |
Iron (mg/l) | 5.0 | 0.05 | 0.3 |
4.6 Setelah selesai kami membuat lawatan dikawasan logi tersebut kami dijamu sedikit jamuan ringan.Pegawai-pegawai dari Loji Rawatan Air Chicha begitu ramah melayan kami semua. Tiga puluh minit bas USM yang membawa kami tiba di Loji Rawatan Air Chicha dan kami bertolok pulang ke USM kampus kesihatan.
5.0 PENUTUP
Konklusinya, lawatan ini telah banyak memberikan kami kesedaran dalam menjaga kualiti air. Kami juga dapat mengetahui mengenai cara-cara untuk menjaga kualiti air yang disalurkan kepada seluruh warga penduduk Kelantan. Pendekatan sebegini dapat memberi kesedaran kepada pelajar tentang kepentingan air dalam kehidupan seharian. Justeru itu, pelbagai inisiatif perlu diambil oleh pihak universiti untuk memperbanyakkan lagi aktiviti lawatan ke loji rawatan air ini kerana lawatan sebegini dapat memberikan faedah serta pengalaman yang berguna kepada para pelajar.
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assightment bio.....
nie dia.... assightment bio aqu... tajuknyer... plasma membrane.... hehehehe macam belajo form 4 balik lah... tapikan.... urm.... x pe ah.... tgk aje lah aqunyer assightment nie.....( sory yerk... sbb aqu baru lagi kat blog nie... so aqu x tau kenape gambor yg aqu letak jadi petak2 putih jer... sory yerk... hehehe.. aqu x leh nak selesaikan masalah nie deeeeeeeeeeeee..... hahahaha)
Define cell membrane
Describe the characteristic of the cell membrane with the help membrane with the help of the diagram
Explain types of transport of the cell
All living cells example prokarytic and eukaryotic have a plasma membrane that encloses their contents and serves as semi – pronous barrier to the outside environtment
The membrane acts as boundary.
It is because membrane holding the cell constituents together and keeping other substances from entering.
Plasma membrane also called the Cell Membrane or plasmalemma.
Plasma membrane is one of the biological membrane that separating the interior of a cell from the outside environment
Cell membrane or plasma membrane are surrounds all cell and it is selectively permeable.
Plasma membrane controlling the movement of substance in and out of the cell.
Plasma membrane is permeable to specific molecules and allows nutrients other essential elements to enter the cell and waste materials to leave the cell.
For example oxygen, carbon dioxide, and water are able to pass freely across the membrane , but the passage of large molecules, such as amino acids and sugar is carefully regulated
Plasma membrane contains a wide variety of biological molecules, primarily proteins and also lipid.
The plasma membrane also serve as the attachment point for the intracellular cytoskeleton and also teh extracellular cell wall
Figure 1 Plasma Membrane
It has lipid bilayer
Two back-to-back layers made up three types of lipid molecules – phospholipid , cholesterol , and glycolipids
About 75% of the membrane lipids are phospholipids, lipids that contain phosphorus
Present in smaller amount are cholesterol (about 20%) and various glycolipids ( about 5%) , lipid with attached carbohydrate groups
The bilayer arrangement occurs because the lipids are amphiphatic molecules, which means that they have both polar and nonpolar parts.
In phospholipid the polar parts is the phosphate containing “head”, which is hydrophilic and hydrophobic
The phospholipid molecules orient themselves in the bilayer with their hydrophilic heads facing outward.
The heads face a watery fluid on either side – cytosol on the inside and extracellular fluid on the outside
The hydrophobic fatty acids tails in each half of the bilayer point towards one another, forming nonpolar, hydrophobic region in the membrane interior
It contains proteins
That can act as pumps, channels, receptors, enzymes or structural components
Integral proteins act as carriers, selectively moving a polar substance or ion from one side of the membrane to the other
Most integral proteins are transmembrane proteins, which means they span the entire lipid bilayer and protrude into both the cytosol and extacellular fluid.
A few integral protein are tightly attached to one side of the bilayer by covalent bonding to fatty acids.
Like membrane lipids, integral membrane proteins are amphitatic.
Their hydrophilic regions protrude into either the watery extracellular fluid or the cytosol, and their hydrophobic regions extend among the fatty acids tails
Peripheral proteins are not as firmly embedded in the membrane. They associate more loosely with the polar head of membrane lipids or with integral proteins at the inner or outer surface of the membrane
Many membrane proteins are glycoproteins, proteins with carbohydrate groups attached to the ends that protrude into the extracellular fluid.
In addition, peripheral proteins help support the plasma membrane, anchor integral proteins, and participate in mechanical activities such as moving materials and organelles within cells, changing cell shape in dividing and muscle cells, and attaching cells to another
It is semipermeable
Some particles can pass through it easily based on concentrations gradients or other factors
The factors that determine the permeability of a molecule across the plasma membrane are polarity , charge and size
The permeability of the plasma membrane to different substance varies.
Plasma membrane permit some substance to pass more readily than other.
The lipid bilayer portion of the membrane is permeable to nonpolar, uncharged molecules. Such as oxygen, carbon dioxide, and steroids
But is impermeable to ions and large, uncharged polar molecules such as glucose
The slight permeability to water and urea is an unexpected property since they are polar molecules
It has potential
Which means a voltage – the difference in charge between the extracellular fluid and intracellular fluid
Transport of the material across the plasma membrane is essential to the life of a cell
Certain substance must move into the cell to support metabolic reactions
Substance generally move across cellular membrane via transport process that can be classified as passive or active, depending on whether they require cellular energy
In passive process, a substance moves down it concentration or electrical gradient to cross the membrane using only its own kinetic energy
Kinetic energy is intrinsic to the particles that are moving
There is no input of energy from the cell, example is simple diffusion
In active process, cellular energy is used to drive the substance against its concentration or electrical gradient
The cellular energy used is usually in the form of ATP, example is active transport.
PASSIVE PROCESSES
THE PRINCIPLE OF DIFFUSION
Diffusion is a passive process in which the random mixing of particle in asolution occurs because of the particle in a solution occurs because of the particles kinetic energy
If a particular solute is present in high concentration in one area of a solution and in low concentration in another area, solute molecules will diffuse toward the area of lower concentration
Some time, the particles become evenly distributed throughout the solution is said to be at equilibrium
The particle continue to move about randomly due to their kinetic energy, but their concentration do not change.
SIMPLE DIFFUSION
Simple diffusion is passive process in which substance move freely through the lipid bilayer of the plasma membrane of cell without the help of membrane transport proteins
Nonpolar, hydrophobic molecules move across the lipid bilayer through the process of simple diffusion
some molecules include oxygen, carbon dioxide, and nitrogen gases and fat-soluble vitamins ( A,D,E and K)
small, uncharged polar molecules such as water, urea and small alcohols also pass through the lipid bilayer by simple diffusion.
simple diffusion through the lipid bilayer is important in the movement of oxygen and carbon dioxide between blood and body cell and between blood and air within the lungs during breathing
it also is the route for absorption of some nutrients and excretion of some waste by body cells
FACILITATED DIFFUSION
Solute that are too polar or highly charged to move through the lipid bilayer by simple diffusion can croos the plasma membrane by a passive process called facilitated diffusion
In this process, an integral membrane protein assists a specific substance across the membrane
The integral membrane protein can be either a membrane channel or a carrier
CHANNEL – MEDIATED FACILITATED DIFFUSION IN CHANNEL MEDIATED FACILITATED DIFUSSION
A solute moves down its concentration gradient across the lipid bilayer through a membrane channel
Most membrane channels are ion channels integral transmembrane proteins that allow passage of small, inorganic ions that are too hydrophilic to penetrate the nonpolar interior of the lipid bilayer
Diffusion of ions through channels is generally slower than free diffusion though the lipid bilayer because channel occupy a smaller fraction of the membrane total surface area than lipids.
A channel is said to be gated when part of the channel protein acts as a “plug” or “gate” changing shape in one way to open the pore and in another way to close it
Some gated channels randomly alternate between the open and closed position other are regulated by chemical or electrical changes inside and outside of the cell.
The plasma membrane of different types of cells may have different number of ion channels and thus display different permeabilities to various ions
CHANNEL – MEDIATED FACILITATED DIFFUSION IN CARRIER MEDIATED FACILITATED DIFUSSION
A carrier is used to move a solute down its concentration gradient across the plasma membrane
The solute binds to a specific carrier undergoes in change a shape
The solute binds more often to the carrier on the side of the membrane with a higher concentration of solute.
The rate of carrier – mediated facilitated diffusion is determine by the steepness of the concentration gradient across the membrane
Substance that move across the plasma membrane by carrier-mediated facilitated diffusion include glucose, fructose, galactose and some vitamins.
Glucose enters many body cells by carrier-mediated facilitated diffusion
The selective permeability of the plasma membrane is often regulated to achieve homeostasis.
With more glucose carrier available, body cells can pick up glucose from the blood more rapidly
An inability to produce or utilize insulin is called diabetes mellitus
OSMOSIS
Osmosis is the type of diffusion in which there is net movement of a solvent through a selectively permeable membrane.
Osmosis is passive process
Passive movement of water molecules across a selectively permeable membrane from an area of higher water concentration to an area of lower water concentration
Osmosis occurs only when a membrane is permeable to water but is not permeable to certain solutes
The solution with the impermeable solute also exerts a force called the osmotic pressure
The osmotic pressure of a solution is proportional to the concentration of the solute particles that cannot cross the membrane- the higher the solute concentration, the higher the solution osmotic
ACTIVE PROCESSES
Such solutes may be able to cross the membrane by a process called active transport
Active transport is consider an active process because energy is required for carrier proteins to move solute across the membrane against a concentration gradient
Solute actively transported across the plasma membrane include several ion
PRIMARY ACTIVE PROCESSES
In primary active transport, energy derived from hydrolysis of ATP changes the shape of a carrier protein, which ‘pumps’ a substance across a plasma membrane against its concentration gradient
Carrier proteins that mediate primary active transport are often called pumps.
A typical body cell expends about 40% of the ATP it generates on primary active transport
The most prevalent primary active transport mechanism expels sodium ions (Na+) from cells and brings potassium ions (K+) in.
The different concentrations of Na+ and K+ in cytosol and extracellular fluid are crucial for maintaining normal cell volume and for ability of some cell to generate electrical signals such as action potentials
By helping to maintain normal tonicity on each side of the plasma membrane, the sodium-potassium pumps ensure that cells neither shrink nor swell due to the movement of water by osmosis out of or into cells
SECONDARY ACTIVE PROCESSES
In secondary active transport, the energy stored in a Na+ or H+ concentration gradient is used to drive other substance across the membrane against on their own concentration gradients.
Because a Na+ or H+ gradient is established by primary active transport, secondary active transport indirectly uses energy obtained from the hydrolysis of ATP
Secondary active transport proteins harness the energy in the Na+ concentration gradient by providing routes for Na+ to leak into cells
If these transporters move two substances in the same direction they are called symporters; antiporters in contrast, move two substances in opposite direction across the membrane
TRANSPORT IN VESICLES
A vesicle as noted earlier, is a small, spherical sac.
A variety of substance are transported in vesicle from one structure to another within cells
Vesicles also import materials from and release materials into extracellular fluid.
During endocytosis, material move into a cell in a vesicle formed from the plasma membrane
In exocytosis, materials move out of a cell by the fusion with the plasma membrane of vesicles formed inside the cell
Thus, transport in vesicles is an active process
Phagocytosis is a form of endocytosis in which the cell engulfs large solid particles, such as worn-out cell
Only a few body cells, termed phagocytes, are able to carry out phagocytosis.
Most body cells carry out bulk-phase endocytosis, also called pinocytosis a form of endocytosis in which tiny droplets of extracellular fluid are taken up.
EXOCYTOSIS
In contrast with endocytosis, which brings materials into a cell, exocytosis releases materials from a cell.
All cells carry out exocytoses, but it is especially important in two types of cells
(1) Secretory cells thet liberate digestive enzymes, hormones, mucus, or other secreation
(2) Nerve cell that release substances called neutransmitters
In some case waste are also released by exocytosis
Segments of the plasma membrane lost through endocytosis are recovered or recycled by exocytosis
Membrane exchange is quite extensive in certain cells
EXOCYTOSIS
Transport in vesicles may also be used to successively move a substance into, across, and out of a cell
This active process called transcytosis, vesicles undergo endocytosison one side of a cell, move across the cell, and then undergo exocytosis on the opposite side
TRANSPORT OF MATERIALS INTO AND OUT OF CELLS
TRANSPORT PROCESS | DESCRIPTION | SUBSTANCE TRANSPORTED |
Passive processes | movement of substance down a concentration gradient until equilibrium is reached | |
Diffusion | The movement of molecules or ions down a concentration gradient due to their kinetic energy until they reach equilibrium | |
Simple diffusion | Passives movement of a substance down its concentration gradient through the lipid bilayer of the plasma membrane without the help of membrane transport proteins | Nonpolar, hydrophobic solute, polar molecules, charged solute |
Facilitated diffusion | Passive movement of a substance down its concentration gradient through the lipid bilayer by transmembrane proteins that function as channels or carriers | Polar or charged solutes solvent |
Osmosis | Passive movement of water molecules across a selectively permeable membrane from an area of higher water concentration to an area of lower water concentration | Solvent: water in living systems |
Active processes | Movement of substances against a concentration gradient requires cellular energy in the form of ATP | |
Active transport | Active process in which a cell expends energy to move a substance across the membrane against its concentration gradient by transmembrane proteins that function as carriers | Polar or charged solutes |
Primary active transport | Active process in which a substance moves across the membrane against its concentration gradient by pumps that use energy supplied by hydrolysis of ATP | Na+, K+, H+ and other ions |
Secondary active transport | Coupled active transport of two substances across the membrane using energy supplied | Antiport: h+ out of cell, Ca2+ Symport: glucose, amino acids |
Transport in vesicles | Active process in which substance move into or out of cells in vesicles that bud from the plasma membrane | |
endocytosis | Movement of substances into a cell in vesicles | |
Receptor-mediated endocytosis | Ligand-receptor complexes trigger infolding of a clathrin-coated pit that forms a vesicle containing ligands | Ligands: transferring, low density lipoproteins |
phagocytosis | “cell eating” movement of asolid particle into a cell after pseudopods engulf it to form a phagosome | Bacteria, virus and aged or dead cell |
Bulk-phase endocytosis | “cell drinking” movement of extracellular fluid into a cell by infolding of plasma membrane to form a vesicle | Solute in extracellular fluid |
Exocytosis | Movement of substances out of a cell in secretory vesicles that fuse with the plasma membrane and release their contents into the extracellular fluid | Neurotransmitter, hormones, and digestive enzymes |
transcytosis | Movement of asubstance through a cell as a result of endocytosis on one side and exocytosis on the opposite side | antibodies |
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